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Orphan Receptor Antibodies

The sequencing of the human genome has allowed NC-IUPHAR to catalog all of the human gene sequences potentially encoding GPCRs, excluding sensory receptors. In addition to established transmitter systems, the classification in the Guide to PHARMACOLOGY also includes ‘orphan’ GPCRs where the endogenous ligand(s) is not known. Considerable progress has been made in screening artificially expressed receptors to identify the cognate endogenous ligand.

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GPR62 (non-phospho), G protein-coupled Receptor 62 Antibody
GPR62 (non-phospho), G protein-coupled...
The non-phospho-GPR62 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human GPR62. It can be used to detect total GPR62 receptors in Western blots independent of phosphorylation. The GPR62 antibody...
£ 335.00 *
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Validation of the MRGPRX2 Receptor in transfected HEK293 cells
MRGPRX2 (non-phospho), MRGPRX2 Mas-related...
The non-phospho-MRGPRX2 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human MRGPRX2. It can be used to detect total MRGPRX2 receptors in Western blots independent of phosphorylation. The MRGPRX2...
£ 335.00 *
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Validation of the GPR3 Receptor in transfected HEK293 cells
GPR3 (non-phospho), G protein-coupled Receptor...
The non-phospho-GPR3 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human GPR3. It can be used to detect total GPR3 receptors in Western blots independent of phosphorylation. The GPR3 antibody can...
£ 335.00 *
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pT427/pS429-GPR75 (IHC grade phospho-GPR75 Antibody)
pT427/pS429-GPR75 (IHC grade phospho-GPR75...
Threonine427/Serine429 (T427/S429) is a major phosphorylation site of the human GPR75 receptor. The pT427/pS429-GPR75 antibody detects GRK-mediated constitutive phosphorylation of GPR75 when expressed in HEK293 cells.
£ 550.00 *
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Immunohistochemical identification of GPR183 Receptor in human spleen
GPR183 (IHC-grade), Oxysterol Receptor Antibody
The non-phospho-GPR183 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human GPR183. It also detects GPR183 in cultured cells and tissue sections by immunohistochemistry. It can be used to detect...
£ 335.00 *
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Validation of the GPR6 Receptor in transfected HEK293 cells.
GPR6 (non-phospho), G protein-coupled Receptor...
The non-phospho-GPR6 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human GPR6. It can be used to detect total GPR6 receptors in Western blots independent of phosphorylation. The GPR6 antibody can...
£ 335.00 *
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Validation of the GPR12 Receptor in transfected HEK293 cells
GPR12 (non-phospho), G protein-coupled Receptor...
The non-phospho-GPR12 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human GPR12. It can be used to detect total GPR12 receptors in Western blots independent of phosphorylation. The GPR12 antibody...
£ 335.00 *
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Validation of the GPR15 Receptor in transfected HEK293 cells
GPR15 (non-phospho), G protein-coupled Receptor...
The non-phospho-GPR15 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human GPR15. It can be used to detect total GPR15 receptors in Western blots independent of phosphorylation. The GPR15 antibody...
£ 335.00 *
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Validation of the GPR22 Receptor in transfected HEK293 cells
GPR22 (non-phospho), G protein-coupled Receptor...
The non-phospho-GPR22 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human GPR22. It can be used to detect total GPR22 receptors in Western blots independent of phosphorylation. The GPR22 antibody...
£ 335.00 *
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Validation of the GPR26 Receptor in transfected HEK293 cells
GPR26 (non-phospho), G protein-coupled Receptor...
The non-phospho-GPR26 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human GPR26. It can be used to detect total GPR26 receptors in Western blots independent of phosphorylation. The GPR26 antibody...
£ 335.00 *
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Validation of the G protein-coupled receptor 32 in transfected HEK293 cells
GPR32 (non-phospho), G protein-coupled Receptor...
The non-phospho-GPR32 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human GPR32. It can be used to detect total GPR32 receptors in Western blots independent of phosphorylation. The GPR32 antibody...
£ 335.00 *
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Validation of the GPR34 Receptor in transfected HEK293 cells
GPR34 (non-phospho), G protein-coupled Receptor...
The non-phospho-GPR34 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human GPR34. It can be used to detect total GPR34 receptors in Western blots independent of phosphorylation. The GPR34 antibody...
£ 335.00 *
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Validation of the SUCNR1 Receptor in transfected HEK293 cells
SUCNR1/GPR91 (non-phospho), Succinate Receptor...
The non-phospho-SUCNR1 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human SUCNR1. It can be used to detect total SUCNR1 receptors in Western blots independent of phosphorylation. The SUCNR1...
£ 335.00 *
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Validation of the GPR39 Receptor in transfected HEK293 cells
GPR39 (non-phospho), G protein-coupled Receptor...
The non-phospho-GPR39 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human GPR39. It can be used to detect total GPR39 receptors in Western blots independent of phosphorylation. The GPR39 antibody...
£ 335.00 *
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Validation of the GPR97/ADGR3G Receptor in transfected HEK293 cells
GPR97/ADGRG3 (non-phospho), G protein-coupled...
The non-phospho-GPR97/ADGRG3 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human GPR97/ADGRG3. It can be used to detect total GPR97/ADGRG3 receptors in Western blots independent of phosphorylation....
£ 335.00 *
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Validation of the GPR101 Receptor in transfected HEK293 cells
GPR101 (non-phospho), G protein-coupled...
The non-phospho-GPR101 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human GPR101. It can be used to detect total GPR101 receptors in Western blots independent of phosphorylation. The GPR101...
£ 335.00 *
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For more information on orphan receptor pharmacology please refer to the IUPHAR database. For further reading refer to:

Davenport AP, Alexander SP, Sharman JL, Pawson AJ, Benson HE, Monaghan AE, Liew WC, Mpamhanga CP, Bonner TI, Neubig RR, Pin JP, Spedding M, Harmar AJ. International Union of Basic and Clinical Pharmacology. LXXXVIII. G protein-coupled receptor list: recommendations for new pairings with cognate ligands. Pharmacol Rev. 2013 May 17;65(3):967-86. doi: 10.1124/pr.112.007179. PMID: 23686350; PMCID: PMC3698937.

For more information on orphan receptor pharmacology please refer to the  IUPHAR  database. For further reading refer to: Davenport AP, Alexander SP, Sharman JL, Pawson AJ, Benson HE,... read more »
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Orphan Receptor Antibodies

For more information on orphan receptor pharmacology please refer to the IUPHAR database. For further reading refer to:

Davenport AP, Alexander SP, Sharman JL, Pawson AJ, Benson HE, Monaghan AE, Liew WC, Mpamhanga CP, Bonner TI, Neubig RR, Pin JP, Spedding M, Harmar AJ. International Union of Basic and Clinical Pharmacology. LXXXVIII. G protein-coupled receptor list: recommendations for new pairings with cognate ligands. Pharmacol Rev. 2013 May 17;65(3):967-86. doi: 10.1124/pr.112.007179. PMID: 23686350; PMCID: PMC3698937.

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