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Orphan Receptor Antibodies

The sequencing of the human genome has allowed NC-IUPHAR to catalog all of the human gene sequences potentially encoding GPCRs, excluding sensory receptors. In addition to established transmitter systems, the classification in the Guide to PHARMACOLOGY also includes ‘orphan’ GPCRs where the endogenous ligand(s) is not known. Considerable progress has been made in screening artificially expressed receptors to identify the cognate endogenous ligand.

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Validation of the GPR135 Receptor in transfected HEK293 cells.
GPR135 (non-phospho), G protein-coupled...
The non-phospho-GPR135 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human GPR135. It can be used to detect total GPR135 receptors in Western blots independent of phosphorylation. The GPR135...
£ 335.00 *
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NEW
Validation of the GPR142 Receptor in transfected HEK293 cells.
GPR142 (non-phospho), G protein-coupled...
The non-phospho-GPR142 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human GPR142. It can be used to detect total GPR142 receptors in Western blots independent of phosphorylation. The GPR142...
£ 335.00 *
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NEW
Validation of the GPR161 Receptor in transfected HEK293 cells
GPR161 (GP-non-phospho), G protein-coupled...
The non-phospho-GPR161 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human GPR161. It can be used to detect total GPR161 receptors in Western blots independent of phosphorylation. The GPR161...
£ 335.00 *
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NEW
Validation of the GPR151 Receptor in transfected HEK293 cells
GPR151 (non-phospho), G protein-coupled...
The non-phospho-GPR151 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human GPR151. It can be used to detect total GPR151 receptors in Western blots independent of phosphorylation. The GPR151...
£ 335.00 *
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NEW
Validation of the GPR152 Receptor in transfected HEK293 cells.
GPR152 (non-phospho), G protein-coupled...
The non-phospho-GPR152 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human GPR152. It can be used to detect total GPR152 receptors in Western blots independent of phosphorylation. The GPR152...
£ 335.00 *
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NEW
Validation of the GPR156 Receptor in transfected HEK293 cells.
GPR156 (non-phospho), G protein-coupled...
The non-phospho-GPR156 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human GPR156. It can be used to detect total GPR156 receptors in Western blots independent of phosphorylation. The GPR156...
£ 335.00 *
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NEW
Validation of the ADGRD1/GPR133 Receptor in transfected HEK293 cells
ADGRD1/GPR133 (non-phospho), Adhesion Receptor...
The non-phospho-ADGRD1/GPR133 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human ADGRD1/GPR133. It can be used to detect total ADGRD1/GPR133 receptors in Western blots independent of...
£ 335.00 *
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NEW
Validation of the ADGRD1/GPR133 Receptor in transfected HEK293 cells
ADGRD1/GPR133 (GP-non-phospho), Adhesion...
The non-phospho-ADGRD1/GPR133 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human ADGRD1/GPR133. It can be used to detect total ADGRD1/GPR133 receptors in Western blots independent of...
£ 335.00 *
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NEW
Validation of the GPR153 Receptor in transfected HEK293 cells.
GPR153 (non-phospho), G protein-coupled...
The non-phospho-GPR153 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human GPR153. It can be used to detect total GPR153 receptors in Western blots independent of phosphorylation. The GPR153...
£ 335.00 *
Details
NEW
Validation of the mouse GPR62 Receptor in transfected HEK293 cells.
mGPR62 (non-phospho), Mouse G protein-coupled...
The non-phospho-mGPR62 receptor antibody is directed against the distal end of the carboxyl-terminal tail of mouse GPR62. It can be used to detect total GPR62 receptors in Western blots independent of phosphorylation. The GPR62 antibody...
£ 335.00 *
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NEW
Validation of the MRGPRX2 Receptor in transfected HEK293 cells
MRGPRX2 (non-phospho), MRGPRX2 Mas-related...
The non-phospho-MRGPRX2 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human MRGPRX2. It can be used to detect total MRGPRX2 receptors in Western blots independent of phosphorylation. The MRGPRX2...
£ 335.00 *
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NEW
Validation of the MRGPRX2 Receptor in transfected HEK293 cells
MRGPRX2 (GP-non-phospho), MRGPRX2 Mas-related...
The non-phospho-MRGPRX2 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human MRGPRX2. It can be used to detect total MRGPRX2 receptors in Western blots independent of phosphorylation. The MRGPRX2...
£ 335.00 *
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Immunohistochemical varification of GPR139 Receptor antibody in kidney
GPR139 (IHC-grade), G protein-coupled Receptor...
The non-phospho-GPR139 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human GPR139. It can be used to detect total GPR139 receptors in Western blots independent of phosphorylation. The GPR139...
£ 335.00 *
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NEW
Agonist-induced Serine358/Serine360 phosphorylation of the GPR52 Receptor
pS358/pS360-GPR52 (phospho-GPR52 Antibody)
Serine358/Serine360 (S358/S360) is major phosphorylation site of the GPR52 Receptor (GPR52). The pS358/pS360-GPR52 antibody detects phosphorylation in response to agonists. S358/S360 phosphorylation is likely to be involved in efficient...
£ 335.00 *
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NEW
Immunohistochemical identification of MRGPRX3 Receptor in duodenum
MRGPRX3 (IHC-grade), MRGPRX3 Mas-related...
The non-phospho-MRGPRX3 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human MRGPRX3. It can be used to detect total MRGPRX3 receptors in Western blots independent of phosphorylation. The MRGPRX3...
£ 335.00 *
Details
NEW
Validation of the MRGPRX3 Receptor in transfected HEK293 cells
MRGPRX3 (non-phospho), MRGPRX3 Mas-related...
The non-phospho-MRGPRX3 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human MRGPRX3. It can be used to detect total MRGPRX3 receptors in Western blots independent of phosphorylation. The MRGPRX3...
£ 335.00 *
Details
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For more information on orphan receptor pharmacology please refer to the IUPHAR database. For further reading refer to:

Davenport AP, Alexander SP, Sharman JL, Pawson AJ, Benson HE, Monaghan AE, Liew WC, Mpamhanga CP, Bonner TI, Neubig RR, Pin JP, Spedding M, Harmar AJ. International Union of Basic and Clinical Pharmacology. LXXXVIII. G protein-coupled receptor list: recommendations for new pairings with cognate ligands. Pharmacol Rev. 2013 May 17;65(3):967-86. doi: 10.1124/pr.112.007179. PMID: 23686350; PMCID: PMC3698937.

For more information on orphan receptor pharmacology please refer to the  IUPHAR  database. For further reading refer to: Davenport AP, Alexander SP, Sharman JL, Pawson AJ, Benson HE,... read more »
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Orphan Receptor Antibodies

For more information on orphan receptor pharmacology please refer to the IUPHAR database. For further reading refer to:

Davenport AP, Alexander SP, Sharman JL, Pawson AJ, Benson HE, Monaghan AE, Liew WC, Mpamhanga CP, Bonner TI, Neubig RR, Pin JP, Spedding M, Harmar AJ. International Union of Basic and Clinical Pharmacology. LXXXVIII. G protein-coupled receptor list: recommendations for new pairings with cognate ligands. Pharmacol Rev. 2013 May 17;65(3):967-86. doi: 10.1124/pr.112.007179. PMID: 23686350; PMCID: PMC3698937.

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